Global emergence of a multi-drug resistant fungal pathogen, Candida auris

Candida auris, an Emerging Fungal Pathogen

The emerging pathogen “Candida auris” is attracting considerable international attention due to its rising reports, transmission through health professionals, high rate of treatment failure and resistance to multiple antifungal agents, particularly fluconazole. In spite of the global emergence of C. auris, epidemiological data and true prevalence of infections due to this organism are not clear...

Secrets of the antibiotic resistant Candida auris

Most fossils from the Pre-Cambrian that were claimed to perhaps be fungal have proved to be artefacts or otherwise dubious (Hawksworth 2015, Taylor et al. 2015). Some more convincing remains of mycelium-like structures have, however, now been reported from a 2.4 billion-year-old basalt from the Palaeoproterozoic of the Pre-Cambrian in South Africa (Bengston et al. 2017). The basalts were submar...

Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally

Candidiasis, which includes both superficial infections and invasive disease, is the most common cause of fungal infection worldwide. Candida bloodstream infections (BSI) cause significant mortality and elicit a major threat to intensive care unit (ICU) patients [1]. The annual global burden of Candida spp. BSIs is about 400,000 cases, with most cases reported from the developed world. Although...

Rapid and Accurate Molecular Identification of the Emerging Multidrug-Resistant Pathogen Candida auris

Candida auris is an emerging multidrug-resistant fungal pathogen causing nosocomial and invasive infections associated with high mortality. C. auris is commonly misidentified as several different yeast species by commercially available phenotypic identification platforms. Thus, there is an urgent need for a reliable diagnostic method. In this paper, we present fast, robust, easy-to-perform and ...

Emergence and Spread of Candida auris in New York State